With Serena Williams vying to safeguard her World No 1 ranking and Djokovic fighting off a wrist injury, expect to see a few surprises at the fourth and final Grand Slam of the year
Second seed Daniil Medvedev will launch his bid to win his first major title against veteran Frenchman Richard Gasquet.
Defending champion Sloane Stephens was sent packing from the Miami Open on Sunday after a 6-3, 6-2 loss to Germany's Tatjana Maria in the third round.
Despite needing just a month to hurtle from nowhere to 19th in the world rankings, new US Open champion Kim Clijsters has no intention of racking up the air miles to pursue a rise to the top of the standings.
Sam Stosur became the first Australian woman in 38 years to win the U.S. Open when she upset American Serena Williams 6-2, 6-3 on Sunday in an ill-tempered final.
So it is over. Two weeks of intriguing tennis where the world's best competed for the year's first Grand Slam. While the match-fixing report cast a shadow over the start of the Australian Open, the tournament gained momentum as it progressed. Rediff.com encapsulates the best moments from the Rod Laver Arena.
Runner-up Pliskova will move into the top-10 of the world rankings for the first time in her career
IMAGES from Day 7 of the US Open on Sunday
Local favourite Amelie Mauresmo reached the final of the Paris Open with a 6-2, 0-6, 6-1 victory over second seed Jelena Jankovic on Saturday. The Frenchwoman, who won the tournament in 2001 and 2006, next faces Olympic champion Elena Dementieva after the third seed from Russia went through when Serena Williams pulled out injured.
It took less than two brutal hours at Wimbledon on Monday to disprove the theory that Serena and Venus Williams could march back to continue their domination of the grasscourt slam having hardly swung their rackets in anger for months.
The loss of the top two seeds was another huge blow to the Advanta Championships which has already seen the withdrawal of Venus and Serena Williams.
Swiatek downs Gauff to meet Sabalenka in Italian Open final
Top seed Jelena Jankovic was bundled out of the Pan Pacific Open in a 2-6, 7-5, 7-5 defeat by Russian Svetlana Kuznetsova in Friday's quarter-finals. The defeat ended the Serb's hopes of recapturing the world number one ranking from Serena Williams this week following her recent loss to the American in US Open final.
Raducanu stormed into the third round of the Cincinnati Open
Seven-time Grand Slam champion Venus Williams has affirmed that she has no plans to bring down the curtains on her illustrious career and is targeting a place in the American team for the 2020 Tokyo Olympics.
Djokovic will next face Sinner in what will be his 46th Grand Slam semi-final, equalling the record of eight-time champion Roger Federer.
Garbine Muguruza is doing her best to stay grounded ahead of the Australian Open after a breakout 2015 season brought a wave of attention and suggestions that she was a Grand Slam champion in waiting.
American Venus Williams crushed Russia's Maria Sharapova 6-2, 6-2, while her younger sister Serena was upset by Australia's Samantha Stosur in the quarter-finals of the Stanford Classic on Friday.
The Belgian was joined by Svetlana Kuznetsova, Jelena Jankovic and Tatiana Golovin in the semi-finals of the Stuttgart Open.
The Belgian raced to victory in one hour, 22 minutes to become the first woman to win the title without losing a set since Serena Williams in 2002.
American tennis ace Venus Williams has entered the top ten of latest WTA ranking following her victory in the Zhuhai Masters in China.
Tennis Australia announced on Tuesday that the world No. 6 had pulled out because of a back problem.
The American is the latest in a series of top players to withdraw from the first Grand Slam of the year.
American Sofia Kenin counter-punched her way back from a set down against Garbine Muguruza to win her first Grand Slam title at the Australian Open with a 4-6, 6-2, 6-2 win in Melbourne on Saturday.
Osaka battled on gamely before retiring while trailing Kaia Kanepi 7-6(4), 3-0.
'Ms Williams has had multiple on-court implosions in the past and got penalised for them, too.' 'She cried sexism this time perhaps because she knew the atmosphere was ripe for it,' notes Shuma Raha.
Form guide for American Serena Williams ahead of Thursday's US Open semi-final clash against Latvia's Anastasija Sevastova:
The US Open kicks off on August 31 and will be held in its usual home in Flushing Meadows, Queens, but will be played without fans in attendance to limit the spread of the virus.
Images from the US Open women's singles third round matches, at Flushing Meadows, New York, on Friday.
Eighth seed Jabeur faced a tougher time against Russian Gracheva as she survived a double break in the decider to set up a meeting with Olympic gold medallist Belinda Bencic, who got the better of Karolina Muchova 6-3, 4-6, 7-5.